Fill in our contact us form before end of the month and receive €100 off your IVF treatment in Cyprus

Close this search box.
DREAM IVF Cyprus Logo

(Intracytoplasmic Sperm Injection)

Enhance your chances of achieving pregnancy with ICSI

Understanding ICSI

Contemplating ICSI? This technique transcends conventional IVF by skillfully bridging the gap where natural fertilisation falters by directly injecting a single sperm into the heart of the egg. ICSI can improve chances of fertilisation even in cases of severe male factor infertility. Empower your journey to parenthood by exploring the potential of ICSI with Dream IVF Cyprus.

What Is ICSI?

In-Vitro Fertilisation (IVF) is a fertility treatment method that involves the fertilisation of eggs outside the body. During  IVF, your eggs and sperm (or donor eggs and sperm) are carefully mixed together in the embryology laboratory. Upon successful fertilisation, the resulting embryos are nurtured in specialized incubators for up to 5 days, allowing them to develop and reach their optimal stage. From this pool of embryos, the most viable and promising one is carefully selected for transfer back into your uterus, where it can implant and grow, leading to a healthy pregnancy. This process mimics the natural course of fertilisation and implantation that occurs during a typical pregnancy.

ICSI stands for in-vitro fertilisation with intracytoplasmic sperm injection. It is a specialised fertility treatment that involves the fertilisation of eggs outside the body using a microscopic needle to inject a single sperm directly into each egg. 

This technique is particularly beneficial when male infertility is a factor, as it ensures that every egg has the opportunity to be fertilised, even in cases of poor sperm quality or motility. By directly facilitating the fertilisation process, ICSI effectively addresses challenges related to sperm movement or quantity, offering men with sperm-related difficulties the opportunity to achieve fatherhood.

What Is The ICSI Process?

The overall ICSI process is similar to standard IVF, with the primary difference occurring at the fertilisation stage. 

The first few steps of the process remain the same: 

  • Initial investigations and scans
  • Consultation with a fertility specialist
  • Ovarian stimulation
  • Egg collection


However, instead of simply mixing the eggs with sperm and allowing fertilization to occur naturally, ICSI employs ICSI to directly inject a single sperm into each egg. While IVF requires a large quantity of sperm, ICSI utilises just one sperm for each egg.

The fertilised eggs, or embryos, are then cultured for 2 to 5 days in an incubator, allowing them to develop and grow. Once the embryologists have determined the most viable embryo, it is carefully transferred into the uterus. Any remaining good quality embryos can be frozen for future use in subsequent cycles.

When Is ICSI Recommended?

ICSI might be recommended under the following circumstances:

  • Low sperm count
  • Poor sperm motility (reduced sperm movement)
  • Utilising sperm obtained through Surgical Sperm Retrieval
  • High levels of DNA damage in sperm
  • Past unsuccessful fertilisation attempts with conventional IVF
  • When using donor eggs
  • When using frozen eggs


ICSI is particularly effective for addressing male infertility issues, such as low sperm count or poor motility.

ICSI offers a slightly higher success rate than standard IVF, particularly in cases of male infertility. This is due to the direct injection of sperm into the eggs, which significantly increases the likelihood of successful fertilisation.

ICSI success rates can vary, as they depend on various factors including the overall health of both partners and adherence to the recommended treatment plan. 

While generally safe, ICSI may have risks, including multiple pregnancies. Consult with your referred clinic about potential risks before undergoing the procedure. 

Yes, ICSI can be applied for fertilising previously frozen eggs and when using donor eggs.

Unlike traditional IVF, which requires a large quantity of sperm, ICSI uses only one sperm for each egg.

IVF with ICSI treatments typically take about 15 – 20 days (including the time needed for fertility tests before starting treatment).

Yes, it is possible to do PGS testing alongside ICSI. Through PGS (Preimplantation Genetic Screening) embryos are tested for genetic abnormalities before they are implanted in the uterus, which can help minimise the risk of miscarriage and birth defects.

A variety of fertility medications may be used to support IVF with ICSI, including clomiphene citrate, letrozole, injectable gonadotropins, and hyaluronidase. These medications help stimulate ovulation, prepare the uterine lining for implantation, and assist with sperm penetration of the egg.

The specific fertility medications prescribed will depend on your individual needs and circumstances, and only your doctor can advise the appropriate medications for you.

Check out our Blog